Retinopathy of Prematurity

Hello and welcome to Sight Research UK. If you're here, you're likely seeking answers about Retinopathy of Prematurity, perhaps for yourself or someone you care deeply about. We're here to help.

Retinopathy of Prematurity

Retinopathy of Prematurity: What You Need to Know

Hello and welcome to Sight Research UK. If you’re here, you’re likely seeking answers about Retinopathy of Prematurity, perhaps for yourself or someone you care deeply about. We’re here to help.

Approximately XXX,XXX people in the UK currently have sight loss caused by Best Disease, and XX,XXX new cases are diagnosed every year (that’s nearly XXX cases a day). It is the most common cause of sight loss in the developed world and the third most common globally.

Known as ROP, Retinopathy of Prematurity is a condition affecting the eyes of prematurely born infants. In this state, irregular blood vessels grow on the retina, the part of the eye that senses light and sends images to the brain. If not addressed timely, the condition can escalate to severe vision issues or even loss of sight.

ROP often shows no immediate symptoms, making early diagnosis challenging. However, certain signs like crossed eyes, white pupils, or abnormal eye movements might be observed. Regular eye screenings are crucial for early detection.

In ROP, blood vessels in the retina grow in an abnormal pattern, sometimes extending into the vitreous, the jelly-like substance inside the eye. This can cause scarring and even retinal detachment, putting the child’s vision at risk.

Retinopathy Of Prematurity Diagram

The exact causes of ROP are still under study, but premature birth remains a key factor. An undeveloped retina is more susceptible to irregular blood vessel growth. Oxygen therapy, often used in neonatal intensive care, is also a known contributing factor.

Treatment strategies for ROP depend on the severity. Early diagnosis is essential for effective management. Treatment options include:

  • Medication injections
  • Laser therapy
  • Cryotherapy (freezing)

When ROP has advanced, surgical intervention might be necessary. The main surgical procedures are:

  • Scleral buckle
  • Vitrectomy

These surgeries aim to secure the retina in place, preventing further damage.

During the surgery, an ophthalmologist focuses on removing scar tissue and repositioning the retina. This can help avoid additional vision loss. Though not without risks, surgery is often the final option to preserve sight.

Early intervention and regular check-ups are your best tools in effectively managing ROP. We’re constantly funding research to learn more about this condition, and we’re eager to share these advancements with you.

We granted £69,748 to Dr Frank Proudlock, Associate Professor in Ophthalmology at the University of Leicester for a 3-year research project to speed-up and improve the diagnosis of ROP sparing thousands of premature babies from distressing, lengthy and unnecessary examinations. Click here to learn more about it.

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